Small pancreatic cancer diagnosis and prognosis / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 375-379, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-293110
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinicopathological characteristics, diagnostic methods and prognosis of small pancreatic cancer.</p><p><b>METHODS</b>From May 2000 to January 2007, 89 patients with pancreatic cancer underwent surgery in our hospital. Of those, 14 had a tumor < or = 2 cm in diameter (small tumor group), and the other 75 had a tumor >2 cm in diameter (controlled group). The clinicopathological data of all the cases were retrospectively reviewed and analyzed.</p><p><b>RESULTS</b>In the small pancreatic cancer group, CT and MRI detected 66.7% (8/12) and 77.8% (7/9) of the tumors, respectively. Serosal infiltration was found in 2 cases, lymph node involvement in 3 cases, and retroperitoneal infiltration in 3 cases. The follow-up duration of this group was 4-86 months. The overall 3- and 5-year survival rates were 42.8% and 31.7%, while in the control group, the overall 3- and 5-year survival rates were 29.7% and 22.5%, respectively. The multivariate analysis showed that the lymph node involvement, serosal infiltration and retroperitoneal infiltration were independent risk factors (P<0.05). However, the tumor size was not shown to be an independent risk factor (OR value = 1.45, P = 0.971).</p><p><b>CONCLUSION</b>CT and MRI are valuable in detecting small pancreatic cancer. Small pancreatic cancers are likely to have a better prognosis when compared with larger ones. Lymph node metastasis and local infiltration are independent predictors of prognosis but not tumor size.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pancreatic Neoplasms
/
Pathology
/
Retroperitoneal Space
/
Serous Membrane
/
General Surgery
/
Magnetic Resonance Imaging
/
Tomography, X-Ray Computed
/
Proportional Hazards Models
/
Survival Rate
/
Retrospective Studies
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Oncology
Year:
2009
Type:
Article
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