Triterpenes and sterols from Nauclea latifolia / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2511-2514, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-293213
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the chemical constituents of Nauclea latifolia, which is an African folk medicine and collected from Guinea.</p><p><b>METHOD</b>The chemical constituents were isolated by silica gel and Sephadex LH-20 column chromatographies, and structurally elucidated by spectral evidence together with physiochemical properties.</p><p><b>RESULT</b>Twelve compounds including 8 triterpenes and 4 sterols were isolated from the roots of N. latifolia, and their structures were defined as 24-en-cycloartenone (1), ursolic aldehyde (2), quinovic acid (3), rotundic acid (4), 3beta,19alpha,23,24-tetrahydroxyurs-12-en-28-oic acid (5), pyrocincholic acid 3beta-O-beta-D-fucopyranoside (6), quinovic acid 3beta-O-beta-D-glucopyranoside (7), quinovic acid-3b-O-D-glucopyranosyl-(28-->1)-beta-D-glucopyranosyl ester (8), beta-sitosterol (9), stigmastan-3,6-dione (10), stigmast-4-en-6beta-ol-3-one (11) and daucosterol (12) .</p><p><b>CONCLUSION</b>All compounds except for 4,9, andl2 are isolated from this plant for the fist time, while compounds 2, 6, 10, and 11 are isolated from the genus Nauclea for the first time.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plants, Medicinal
/
Sterols
/
Triterpenes
/
Plant Extracts
/
Magnetic Resonance Spectroscopy
/
Chemistry
/
Chromatography
/
Guinea
/
Plant Roots
/
Rubiaceae
Country/Region as subject:
Africa
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2011
Type:
Article
Similar
MEDLINE
...
LILACS
LIS