Expression of trophinin in human oocytes and preimplantation embryos / 南方医科大学学报
Journal of Southern Medical University
;
(12): 122-124, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-293437
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the significance of trophinin expression in human oocytes and preimplantation embryos.</p><p><b>METHODS</b>The expression of trophinin in 9 human oocytes, 16 blastomeres and 12 blastocysts were detected by indirect immunofluorescence assay and observed under laser scanning confocal microscope.</p><p><b>RESULTS</b>Human oocytes, blastomeres and blastocysts were all positive for trophinin expression, and the positivity intensified significantly in the course of the embryonic development (P<0.05).</p><p><b>CONCLUSION</b>Trophinin may play an important role in human embryo implantation by mediating homophilic adhesion between the embryo and the endometrium during the implantation window.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oocytes
/
Blastocyst
/
Cell Adhesion Molecules
/
Microscopy, Confocal
/
Fluorescent Antibody Technique, Indirect
/
Metabolism
Limits:
Female
/
Humans
/
Pregnancy
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2008
Type:
Article
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