Studies on the flavonoids in herb from Scutellaria barbata / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study flavonoids in Scutellaria barbata and elucidate their structures.</p><p><b>METHOD</b>Compounds were isolated and purified by normal column chromatography, paper thin layer chromatography and Sephadex chromatography. The chemical structures were elucidated by ESI mass and NMR spectra.</p><p><b>RESULT</b>Five flavonoids were isolated from S. barbata and identified as apigenin (1), luteolin (2), ethyl-7-O-apigenin-glucuronate (3), apigenin-7-O-beta-glucoside (4), and apigenin-7-O-neohesperidoside (5), in addition to benzyaldehyde (6).</p><p><b>CONCLUSION</b>Flavonoidglycoside (3), (4) and (5) were isolated from S. barbata for the first time.</p>