Effect of the sustained release excipients on the release rate of ginsenoside Rg1 and ginsenoside Rb1 in sustained-release tablet of Panax notoginsenosides / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 944-947, 2004.
Article
in Chinese
| WPRIM
| ID: wpr-293668
ABSTRACT
<p><b>OBJECTIVE</b>To study the influence of the sustained release excipient on the release rate of ginsenoside Rg1 and ginsenoside Rb1 in sustained-release tablet of Panax Notoginsenosides.</p><p><b>METHOD</b>The release rate of ginsenoside Rg1 and ginsenoside Rb1 in different matrix tablets with different excipient (HPMC, EC), different viscosity of EC (RT-50, RT-100), different ratio of EC in matrix tablet were detected.</p><p><b>RESULT</b>All above different factors influence the release rate of ginsenoside Rg1 and ginsenoside Rb1 and brought them different release curve.</p><p><b>CONCLUSION</b>Emphasis should be laid on the different release characteristic of different active compounds in active fraction.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oxazines
/
Plants, Medicinal
/
Tablets
/
Drugs, Chinese Herbal
/
Chemistry
/
Chemistry, Pharmaceutical
/
Delayed-Action Preparations
/
Ginsenosides
/
Excipients
/
Panax
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2004
Type:
Article
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