Study on the production condition of extraction in combination hydrolysis in situ for isolating diosgenin / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 934-937, 2003.
Article
in Zh
| WPRIM
| ID: wpr-293686
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the production technology of extraction in combination hydrolysis in situ for isolating diosgenin from Dioscorea nipponica by orthogonal design.</p><p><b>METHOD</b>The optimum production conditions were investigated with the recovery of diosgenin as an index by extraction in combination hydrolysis in situ, and were compared with the traditional method.</p><p><b>RESULT</b>Extraction in combination hydrolysis in situ conducted in 1.5 mol x L(-1) sulfuric acid of water containing 75% isopropanol at 100 degrees C for 4.5 h could get higher recovery of diosgenin than traditional methods.</p><p><b>CONCLUSION</b>This production technology can get higher recovery of diosgenin, and it is simple, time and money saving.</p>
Full text:
1
Index:
WPRIM
Main subject:
Pressure
/
Sulfuric Acids
/
Temperature
/
Time Factors
/
Chemistry
/
Technology, Pharmaceutical
/
Dioscorea
/
Diosgenin
/
Hydrolysis
/
Methods
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2003
Type:
Article