Effect of ginsenoside Rg2 on chemical myocardial ischemia in rats

Jian-ming TIAN; Hao LI; Jin-mei YE; Wei-fang GUO; Lon-yun LI; Li-ping WANG

Effect of ginsenoside Rg2 on chemical myocardial ischemia in rats / 中国中药杂志

Jian-ming TIAN; Hao LI; Jin-mei YE; Wei-fang GUO; Lon-yun LI; Li-ping WANG.

China Journal of Chinese Materia Medica ; (24): 1191-1192, 2003.

Article in Chinese | WPRIM | ID: wpr-293695

ABSTRACT

ABSTRACT

OBJECTIVETo investigate the protective effect of Ginsenoside Rg2 on Chemical myocardial ischemia.METHODThe models of myocardial ischemia were built in rats with isoproterenol, sodium nitrite,pituitrin. Ginsenoside Rg2 (iv 2.5, 5.0, 10.0 mg x kg(-1)) were intravenously administered.RESULTGinsenoside Rg2 could improve the abnormal electrocardiogram (ECG), reduce the arca of myocardial ischemia and improve the abnormal zymologic value of myocardial.CONCLUSIONGinsenoside Rg2 has inhibitory function on myocardialischemia.

Subject(s)

Animals; Female; Male; Rats; Creatine Kinase; Metabolism; Electrocardiography; Ginsenosides; Pharmacology; Isoproterenol; Malondialdehyde; Metabolism; Myocardial Ischemia; Pathology; Myocardium; Pathology; Panax; Chemistry; Pituitary Hormones, Posterior; Plant Leaves; Chemistry; Plants, Medicinal; Chemistry; Rats, Wistar; Sodium Nitrite; Superoxide Dismutase; Metabolism

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Pharmacology / Pituitary Hormones, Posterior / Plants, Medicinal / Sodium Nitrite / Superoxide Dismutase / Chemistry / Rats, Wistar / Myocardial Ischemia / Plant Leaves Limits: Animals Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2003 Type: Article

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