Your browser doesn't support javascript.
loading
Effect of SspA on the formation of bacterial biofilm covering the surfaces of cardiovascular biomaterial Dacron / 生物医学工程学杂志
Journal of Biomedical Engineering ; (6): 787-791, 2009.
Article in Chinese | WPRIM | ID: wpr-294569
ABSTRACT
This study sought to assess the effect of SspA on the formation of Staphylococcus aureus biofilm extending over the surfaces of Cardiovascular Biomaterial Dacron. SspA was extracted from the surface of staphylococcus aureus biofilm, purified, and then used to influence the adhesion of Staphylococcus aureus and the formation of Staphylococcus aureus biofilm on Dacron biomaterial surfaces. The formation of the Staphylococcus aureus biofilm on cardiovascular biomaterial Dacron surfaces under gradient SspA concentrations was evaluated by confocal laser microscopy. The result revealed that SspA inhibited the formation of Staphylococcus aureus biofilms on cardiovascular biomaterials surfaces effectively, and it was dose dependent. This study indicates that SspA is effective for preventing biomaterial centered infection and this method is conducive to clinical applications.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Physiology / Staphylococcus aureus / Virulence / Biocompatible Materials / Bacterial Adhesion / Serine Endopeptidases / Chemistry / Prosthesis-Related Infections / Polyethylene Terephthalates Language: Chinese Journal: Journal of Biomedical Engineering Year: 2009 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Physiology / Staphylococcus aureus / Virulence / Biocompatible Materials / Bacterial Adhesion / Serine Endopeptidases / Chemistry / Prosthesis-Related Infections / Polyethylene Terephthalates Language: Chinese Journal: Journal of Biomedical Engineering Year: 2009 Type: Article