Study on Fibrovascular Ingrowth into the Intraocular Implant, Medpor(R)
Journal of the Korean Ophthalmological Society
;
: 1310-1322, 2002.
Article
in Korean
| WPRIM
| ID: wpr-29457
ABSTRACT
PURPOSE:
We investigated the effects of bFGF/Sucralfate/Hydron suspension and hyperbaric oxygen on fibrovascular ingrowth into porous implants materials.METHODS:
Eight rabbits underwent bilateral abdominal incision through which porous orbital disc-shaped implants were inserted between abdominal muscles. These implants were either uncoated or coated with suspension of bFGF/Sucralfate/Hydron. Hyperbaric oxygen therapy was performed on 4 selected rabbits for 5 days or 10 days. Implants were harvested after 3 days, 1 week, 2 weeks and 4 weeks.RESULTS:
Enhanced fibrovascular ingrowth was shown in bFGF/Sucralfate/Hydron or hyperbaric oxygen treated implants. bFGF/Sucralfate/Hydron treated implants demonstrated more fibrovascularization than hyperbaric oxygen treated implants.CONCLUSIONS:
Simultaneous therapy of bFGF/Sucralfate/Hydron and hyperbaric oxygen showed more fibrovascularization than separately treated implants.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Orbit
/
Oxygen
/
Fibroblast Growth Factor 2
/
Abdominal Muscles
/
Hyperbaric Oxygenation
Limits:
Animals
Language:
Korean
Journal:
Journal of the Korean Ophthalmological Society
Year:
2002
Type:
Article
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