Research of neuronal structures target localization based on Hilbert-Huang transform for neuronal discharges / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 638-642, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-294602
ABSTRACT
Electrophysiological target localization is the key technology in microelectrode-guided stereotactic neurosurgery for Parkinson's disease (PD). A neuronal discharge signal analysis method based on Hilbert-Huang transform (HHT) was introduced. By decomposing the clinical microelectrode recording (MER) data of PD into intrinsic mode functions (IMFs), the marginal spectrums of IMFs were achieved, and the characteristic factor correlated with brain structure was explored, then the HHT characteristic factor curve of neuronal discharge signals of microelectrode piqure locus could be achieved. The structures of neuronal and boundaries can be distinguished by the characteristic factor curve, and then damage range and damage point can be identified. This method can assist clinicians in ascertaining operation target effectively and researching into the cases of PD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Parkinson Disease
/
Physiology
/
General Surgery
/
Signal Processing, Computer-Assisted
/
Stereotaxic Techniques
/
Cell Biology
/
Electrophysiology
/
Methods
/
Microelectrodes
/
Neurons
Type of study:
Prognostic study
Limits:
Humans
Language:
Chinese
Journal:
Journal of Biomedical Engineering
Year:
2009
Type:
Article
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