Preparation of novel bioactive PCL bone tissue engineering scaffold / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 550-565, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-294619
ABSTRACT
In the present study, porous PCL (poly (epsilon-caprolactone)) scaffolds were prepared through a melted extrusion manufacturing (MEM) machine, and carboxylate groups were formed on the surfaces of specimen by hydrolyzation with NaOH aqueous solutions. Apatite precursor was introduced on the surfaces of specimens with CaCl2 and K2 HPO4 under vacuum condition, and mineralization study was applied to these specimens. The results showed that the hydrophilicity of PCL surface was improved with the introduction of carboxylate groups, and the contact angle of surface was decreased to 26.52 degrees. A dense and uniform bone-like layer was confirmed to be formed on the surface of Ca-P treated specimens after mineralizing for less than 24 h in SBF by SEM and EDAX.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polyesters
/
Biocompatible Materials
/
Bone Regeneration
/
Chemistry
/
Tissue Engineering
/
Guided Tissue Regeneration
/
Tissue Scaffolds
/
Methods
Limits:
Humans
Language:
Chinese
Journal:
Journal of Biomedical Engineering
Year:
2009
Type:
Article
Similar
MEDLINE
...
LILACS
LIS