Intracytoplasmic morphologically selected sperm injection of testicular sperm: clinical outcome in azoospermia patients / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To assess whether intracytoplasmic morphologically selected sperm injection (IMSI) of testicular sperm improves the clinical outcome in patients with azoospermia.</p><p><b>METHODS</b>We performed conventional intracytoplasmic sperm injection (ICSI) for 66 patients diagnosed with azoospermia and IMSI for another 39 using testicular sperm selected at high magnification ( x 6000), and comparatively analyzed the clinical outcomes of the two techniques.</p><p><b>RESULTS</b>There were no statistically significant differences between conventional ICSI and IMSI in the rates of pregnancy (51.52% vs. 56.41%) and implantation (30.67% vs. 35.29%), although the rate of early abortion was lower in the IMSI than in the ICSI group (4.50% vs. 11.76%).</p><p><b>CONCLUSION</b>IMSI of testicular sperm may effect a lower rate of early abortion than conventional ICSI in patients with azoospermia.</p>