Advances in identification of semen stains / 中华男科学杂志
National Journal of Andrology
;
(12): 735-740, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-295007
ABSTRACT
Stain identification has long been a task in forensic biology. The identification of semen stain, one of the most common human stains, can provide crucial information for crime scene reconstruction and forensic investigation. Traditional detection of semen stain depends largely on the microscopic identification of spermatozoa, enzyme activity-based methods or antigen-antibody reactions. These morphological, proteinological and zymological approaches, however, are apparently inadequate in identifying tiny, admixed, degraded or contaminated samples. With the development of transcriptomics and epigenetics, many semen-specific mRNA markers, such as protamine-1 (PRM1) and -2 (PRM2), have been applied to semen and semen stain identification. Messenger RNA profiling shows great promise in identifying tissues as demonstrated by the recognition of specific markers. Further more, studies on tis-sue-specific differential DNA methylation will provide a scrumptious way of identifying difficult samples.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Semen
/
RNA, Messenger
/
Genetic Markers
/
DNA Methylation
/
Forensic Medicine
/
Methods
Limits:
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2010
Type:
Article
Similar
MEDLINE
...
LILACS
LIS