Sdudy on effect of tripterygium on plasma IL-18 content in patients with lupus nephritis / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1075-1077, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-295404
ABSTRACT
<p><b>OBJECTIVE</b>It is to study the effect of tripterygium (TW) on the plasma IL-18 content in patients with lupus nephritis (LN) and its treatment value.</p><p><b>METHOD</b>The patients with LN treated with prednisone were divided into active groupand inactive group with active index. The active group was given tripterygium additionally. The changing of plasma IL-18 and release of nephritis were observed after treatment for three months.</p><p><b>RESULT</b>The level of plasma IL-18 lowered down obviously, urinary protein decreased, LN activity index, hematuria and renal function improved.</p><p><b>CONCLUSION</b>Tripterygium caninhibitroduction of plasma IL-18. It has definite treatment value on controlling LN activity.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood
/
Lupus Nephritis
/
Drugs, Chinese Herbal
/
Chemistry
/
Retrospective Studies
/
Treatment Outcome
/
Interleukin-18
/
Tripterygium
/
Therapeutic Uses
/
Drug Therapy
Type of study:
Observational study
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2008
Type:
Article
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