Study on anti-diabetes active fraction and constituents from Potentilla chinesis / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the active fraction and constituents from Potentilla chinesis.</p><p><b>METHOD</b>Tested fractions were obtained by different solvent-partition from 95% ethanol-extracts of P. chinesis, and tested compound was isolated by repeated chromatography. Anti-diabetes experiment was taken by using alloxan-induced diabetic mice.</p><p><b>RESULT</b>The fraction F and the tested compound revealed obvious difference comparing with the control group (P <0.01).</p><p><b>CONCLUSION</b>Fraction F and potentilla flavone revealed the significant hypoglycemic effect in alloxan-induced diabetic mice.</p>