Evaluation on the visual inspection with Lugol's iodine in cervical cancer screening program / 中华流行病学杂志
Chinese Journal of Epidemiology
;
(12): 15-18, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-295614
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate visual inspection with Lugol's iodine (VILI) in cervical cancer screening program and to provide evidence for designing a cervical cancer screening algorithm in high risk areas of existing low-resource settings to reduce the incidence and mortality of cervical cancer.</p><p><b>METHODS</b>Women in Yangcheng county, Shanxi province were screened with VILI, colposcopy, liquid-based cytology test and human papilloma virus (HPV) DNA test. The efficacy of different screening tests was compared by Youden's index based on the pathology as the gold standard.</p><p><b>RESULTS</b>In the population being screened, the mean age was 40.80 +/- 10.75 years old. Based on pathological findings, 4.35% (32/735) of the subjects had >or= CIN (cervical intraepithelial neoplasia) II. The sensitivity and specificity for the VILI test (>or= positive) were 53.13 and 82.19, while 56.25 and 79.09 were for colposcopy (>or= low grade dysplasia) respectively. Comparing by the Youden's indexs, there was no statistically significant difference (P > 0.05) between VILI and colposcopy. However, statistical significant difference (P < 0.05) was found between VILI and liquid-based cytology test and HPV DNA test. In addition, there was no statistically significant difference (P > 0.05) found between the experienced doctors and the newly-trained doctors working in the field station.</p><p><b>CONCLUSION</b>With low sensitivity when using microscope but low cost of equipments, VILI can be one of the primary screening tests in China's rural area with low-resource settings if the screening frequency is to be increased.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Socioeconomic Factors
/
Program Evaluation
/
Uterine Cervical Dysplasia
/
Uterine Cervical Neoplasms
/
China
/
Rural Health
/
Epidemiology
/
Incidence
/
Sensitivity and Specificity
/
Diagnosis
Type of study:
Diagnostic study
/
Evaluation studies
/
Health economic evaluation
/
Incidence study
/
Prognostic study
/
Screening study
Limits:
Adult
/
Female
/
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Epidemiology
Year:
2006
Type:
Article
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