A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer

Li-Sha CHEN; An-Xin WANG; Bing DONG; Ke-Feng PU; Li-Hua YUAN; Yi-Min ZHU

A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer / 癌症

Li-Sha CHEN; An-Xin WANG; Bing DONG; Ke-Feng PU; Li-Hua YUAN; Yi-Min ZHU.

Chinese Journal of Cancer ; (12): 564-572, 2012.

Article in English | WPRIM | ID: wpr-295887

ABSTRACT

ABSTRACT

According to the cancer stem cell theory, cancers can be initiated by cancer stem cells. This makes cancer stem cells prime targets for therapeutic intervention. Eradicating cancer stem cells by efficient targeting agents may have the potential to cure cancer. In this review, we summarize recent breakthroughs that have improved our understanding of cancer stem cells, and we discuss the therapeutic strategy of targeting cancer stem cells, a promising future direction for cancer stem cell research.

Subject(s)

Humans; Antineoplastic Agents; Pharmacology; Therapeutic Uses; Biomarkers, Tumor; Metabolism; Cell Differentiation; Drug Carriers; Gold; Nanostructures; Neoplasms; Drug Therapy; Metabolism; Pathology; Neoplastic Stem Cells; Metabolism; Pathology

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Pharmacology / Neoplastic Stem Cells / Drug Carriers / Biomarkers, Tumor / Cell Differentiation / Therapeutic Uses / Nanostructures / Drug Therapy / Gold Limits: Humans Language: English Journal: Chinese Journal of Cancer Year: 2012 Type: Article

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