Antiphospholipid Syndrome and Vascular Ischemic (Occlusive) Diseases: An Overview
Yonsei Medical Journal
;
: 901-926, 2007.
Article
in English
| WPRIM
| ID: wpr-29618
ABSTRACT
Antiphospholipid syndrome (APS) is primarily considered to be an autoimmune pathological condition that is also referred to as "Hughes syndrome". It is characterized by arterial and/or venous thrombosis and pregnancy pathologies in the presence of anticardiolipin antibodies and/or lupus anticoagulant. APS can occur either as a primary disease or secondary to a connective tissue disorder, most frequently systemic lupus erythematosus (SLE). Damage to the nervous system is one of the most prominent clinical constellations of sequelae in APS and includes (i) arterial/ venous thrombotic events, (ii) psychiatric features and (iii) other non- thrombotic neurological syndromes. In this overview we compare the most important vascular ischemic (occlusive) disturbances (VIOD) with neuro-psychiatric symptomatics, together with complete, updated classifications and hypotheses for the etio-pathogenesis of APS with underlying clinical and laboratory criteria for optimal diagnosis and disease management.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arterial Occlusive Diseases
/
Cerebrovascular Disorders
/
Antiphospholipid Syndrome
/
Antibodies, Antiphospholipid
/
Lupus Erythematosus, Systemic
Limits:
Humans
Language:
English
Journal:
Yonsei Medical Journal
Year:
2007
Type:
Article
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