Surveys in Areas of High Risk of Iodine Deficiency and Iodine Excess in China, 2012-2014: Current Status and Examination of the Relationship between Urinary Iodine Concentration and Goiter Prevalence in Children Aged 8-10 Years / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 88-96, 2017.
Article
in English
| WPRIM
| ID: wpr-296511
ABSTRACT
<p><b>OBJECTIVE</b>We aimed to evaluate goiter prevalence and iodine nutritional status in areas with high levels of water iodine; to monitor the prevalence of iodine deficiency disorders (IDD) in areas at high risk of IDD; and to compare the prevalence of goiter and urine iodine (UI) concentrations between children living in the two areas.</p><p><b>METHODS</b>Based on surveillance from 2012-2014, we analyzed the concentration of UI and prevalence of goiter in 8-10-year-old children from 12 high-risk IDD provinces, and from 8 provinces and municipalities with excessive water iodine. We calculated goiter prevalence for each UI level according to World Health Organization (WHO) standards and constructed predictive prevalence curves.</p><p><b>RESULTS</b>The goiter prevalence and median UI of children from areas with high water iodine were not optimal, being above the WHO standards (5% and 100-199 μg/L, respectively), whereas those in high-risk areas fell within the standard. UI and goiter prevalence exhibited a U-shaped relationship in high-risk endemic areas and a parabolic relationship in areas of iodine excess.</p><p><b>CONCLUSION</b>Iodine surplus in high-iodine areas leads to high goiter prevalence and UI. However, in high-risk areas, UI was optimal and goiter prevalence met the national criteria for IDD elimination.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Urine
/
China
/
Epidemiology
/
Prevalence
/
Risk Factors
/
Dose-Response Relationship, Drug
/
Goiter
/
Iodine
Type of study:
Etiology study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Child
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Biomedical and Environmental Sciences
Year:
2017
Type:
Article
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