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Alcohol Drinking, Dyslipidemia, and Diabetes: A Population-based Prospective Cohort Study among Inner Mongolians in China / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences ; (12): 555-562, 2016.
Article in English | WPRIM | ID: wpr-296568
ABSTRACT
<p><b>OBJECTIVE</b>No previous studies have evaluated the association between dyslipidemia, alcohol drinking, and diabetes in an Inner Mongolian population. We aimed to evaluate the co-effects of drinking and dyslipidemia on diabetes incidence in this population.</p><p><b>METHODS</b>The present study was based on 1880 participants from a population-based prospective cohort study among Inner Mongolians living in China. Participants were classified into four subgroups according to their drinking status and dyslipidemia. Multivariate logistic regression analysis and receiver operating characteristic (ROC) curves were used to evaluate the association between alcohol drinking, dyslipidemia, and diabetes.</p><p><b>RESULTS</b>During the follow-up period, 203 participants were found to have developed diabetes. The multivariable-adjusted odds ratios (95% confidence interval) for the incidence of non-dyslipidemia/drinkers, dyslipidemia/non-drinkers, and dyslipidemia/drinkers in diabetic patients were 1.40 (0.82-2.37), 1.73 (1.17-2.55), and 2.31 (1.38-3.87), respectively, when compared with non-dyslipidemia/non-drinkers. The area under the ROC curve for a model containing dyslipidemia and drinking status along with conventional factors (AUC=0.746) was significantly (P=0.003) larger than the one containing only conventional factors (AUC=0.711).</p><p><b>CONCLUSION</b>The present study showed that dyslipidemia was an independent risk factor for diabetes, and that drinkers with dyslipidemia had the highest risk of diabetes in the Mongolian population. These findings suggest that dyslipidemia and drinking status may be valuable in predicting diabetes incidence.</p>
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Alcohol Drinking / China / Epidemiology / Incidence / Prospective Studies / Risk Factors / ROC Curve / Follow-Up Studies / Diabetes Mellitus / Dyslipidemias Type of study: Etiology study / Incidence study / Observational study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Biomedical and Environmental Sciences Year: 2016 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Alcohol Drinking / China / Epidemiology / Incidence / Prospective Studies / Risk Factors / ROC Curve / Follow-Up Studies / Diabetes Mellitus / Dyslipidemias Type of study: Etiology study / Incidence study / Observational study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Biomedical and Environmental Sciences Year: 2016 Type: Article