Research advances in immunological pathogenesis of immunoglobulin A vasculitis / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 837-840, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-297198
ABSTRACT
Immunoglobulin A (IgA) vasculitis is the most common leukocytoclastic small-vessel vasculitis in children and mainly involves the small vessels in the skin, joints, digestive tract, and kidneys. Its pathogenesis is still unclear. Currently, it is believed that environmental factors can cause autoimmune dysfunction and lead to the deposition of IgA-containing immune complexes on the wall of arterioles on the basis of genetic factors. This article reviews the research advances in the role of immune factors in the pathogenesis of IgA vasculitis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Autoantibodies
/
Vasculitis
/
Glycosylation
/
Complement System Proteins
/
Immunoglobulin A
/
Immunoglobulin E
/
Cytokines
/
Allergy and Immunology
/
Metabolism
Type of study:
Etiology study
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2017
Type:
Article
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