Research advances in the protective effect of all-trans retinoic acid against podocyte injury / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 719-723, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-297220
ABSTRACT
All-trans retinoic acid (ATRA) is a vitamin A derivative and plays an important role in the regulation of cell aggregation, differentiation, apoptosis, proliferation, and inflammatory response. In recent years, some progress has been made in the role of ATRA in renal diseases, especially its protective effect on podocytes. This article reviews the research advances in podocyte injury, characteristics of ATRA, podocyte differentiation and regeneration induced by ATRA, and the protective effect of ATRA against proliferation, deposition of fibers, and apoptosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Physiology
/
Tretinoin
/
Cell Differentiation
/
Apoptosis
/
Cytoprotection
/
Cell Proliferation
/
Podocytes
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2017
Type:
Article
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