Effect of platelet-activating factor on sperm function / 中华男科学杂志
National Journal of Andrology
;
(12): 538-541, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-297687
ABSTRACT
Platelet-activating factor (PAF) is a unique and novel signaling phospholipid that has pleiotropic biologic properties in addition to platelet activation. Recent studies show that this novel compound plays a significant role in male reproduction and sperm function. PAF binds surface special receptors inducing the formation of inositol triphosphate (IP3) and diacylglycerol (DAG) and increasing intracellular calcium. The concentrations of sperm-derived PAF may help predict sperm motility and fertilization potential, which may serve as a valuable marker for assessing male fertility. Exogenous PAF can improve sperm motility, acrosome reaction and pregnancy rates in human intrauterine inseminations.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Physiology
/
Sperm Motility
/
Spermatozoa
/
Platelet Activating Factor
/
Fertilization in Vitro
Type of study:
Prognostic study
Limits:
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2007
Type:
Article
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