Expression of kinase insert domain-containing receptor in prostate adenocarcinoma / 中华男科学杂志
National Journal of Andrology
;
(12): 324-326, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-297732
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the correlation between the expression of the kinase insert domain-containing receptor (KDR) and the histological grade of prostate adenocarcinoma.</p><p><b>METHODS</b>Forty-eight samples of prostate adenocarcinoma tissues and 20 samples of benign prostatic hypertrophy (BPH) tissues were studied by LsAB immunohistochemical staining.</p><p><b>RESULTS</b>The positive expression rate of KDR was 73% in prostate adenocarcinoma and 30% in BPH. The expression of KDR was stronger in prostate adenocarcinoma, and there was no relationship between staining intensity and the histological grade of carcinoma.</p><p><b>CONCLUSION</b>KDR, expressed more highly in prostate adenocarcinoma, promises to be a new target in the treatment of prostate adenocarcinoma.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prostatic Hyperplasia
/
Prostatic Neoplasms
/
Adenocarcinoma
/
Receptors, Vascular Endothelial Growth Factor
/
Vascular Endothelial Growth Factor Receptor-2
/
Metabolism
Limits:
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2007
Type:
Article
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