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Advances in the studies of epididymal protease inhibitor--Eppin / 中华男科学杂志
National Journal of Andrology ; (12): 168-170, 2007.
Article in Chinese | WPRIM | ID: wpr-297759
ABSTRACT
The epididymal protease inhibitor (Eppin) abounds in human semen and on the surface of human spermatozoa, specifically produced by the testis and epididymis. Recombinant Eppin has effected infertility in the immunized monkey and promises to be an effective vaccine for human immunocontraception. This article reviews the advances in the studies of Eppin gene and protein construction and its molecular mechanism of causing immunologic infertility and regulating PSA hydrolysis of Semenogelin.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Physiology / Primates / Chemistry / Vaccines, Contraceptive / Seminal Vesicle Secretory Proteins / Allergy and Immunology / Proteinase Inhibitory Proteins, Secretory / Genetics / Infertility, Male Limits: Animals / Humans / Male Language: Chinese Journal: National Journal of Andrology Year: 2007 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Physiology / Primates / Chemistry / Vaccines, Contraceptive / Seminal Vesicle Secretory Proteins / Allergy and Immunology / Proteinase Inhibitory Proteins, Secretory / Genetics / Infertility, Male Limits: Animals / Humans / Male Language: Chinese Journal: National Journal of Andrology Year: 2007 Type: Article