Bioinformatic identification and analysis of Schistosoma japonicum adenine phosphoribosyltransferase / 南方医科大学学报
Journal of Southern Medical University
;
(12): 272-275, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-298189
ABSTRACT
<p><b>OBJECTIVE</b>To identify adenine phosphoribosyltransferases in Schistosoma japonicum and analyze their structural features.</p><p><b>METHODS</b>Based on the accessible transcriptome and proteomic data, the S. japonicum adenine phosphoribosyl transferases were identified using bioinformatics approaches including bi-directional homology comparison, domain search and phylogenetic analysis. Homology modeling was also performed to describe the structural features of the proteins.</p><p><b>RESULTS AND CONCLUSION</b>Two homologue sequences of adenine phosphoribosyltransferase were obtained from S. japonicum, and the EST abundance, physico-chemical properties and three-dimensional structures of them were also acquired.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phylogeny
/
Protein Conformation
/
Schistosoma japonicum
/
Adenine Phosphoribosyltransferase
/
Models, Molecular
/
Helminth Proteins
/
Chemistry
/
Computational Biology
/
Genetics
/
Isoenzymes
Limits:
Animals
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2007
Type:
Article
Similar
MEDLINE
...
LILACS
LIS