Chemical constituents of the non-alkaloid fraction of Uncaria macrophylla / 南方医科大学学报
Journal of Southern Medical University
;
(12): 226-227, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-298198
ABSTRACT
<p><b>OBJECTIVE</b>To analyze the chemical constituents of the non-alkaloid fraction of Uncaria macrophylla.</p><p><b>METHODS</b>The constituents were separated and purified by silica gel chromatography and recrystalization, and their structures were identified by infrared, mass and nuclear magnetic resonance spectrometry.</p><p><b>RESULTS</b>Six compounds were isolated from the non-alkaloid fraction of Uncaria macrophylla, whose structures were identified as beta-sitosterol, beta-daucosterol, ursolic acid, alpha-amyrin acetate, 3beta, 6beta, 23-trihydroxyurs-12-en-28-oic acid, 3beta-hydroxyurs-12-en-27, and 3beta-hydroxyurs-12-en-27, 28-dioic acid, respectively.</p><p><b>CONCLUSIONS</b>Ursolic acid is the main component in the non-alkaloid fraction of Uncaria macrophylla. Alpha-amyrin acetate and 3beta-hydroxyurs-12-en-27, 28-dioic acid are isolated and characterized for the first time from this plant.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oleanolic Acid
/
Triterpenes
/
Chemistry
/
Uncaria
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2007
Type:
Article
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