Effects of Sarcandra glabra extract on immune activity in restraint stress mice / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 100-103, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-298454
ABSTRACT
<p><b>OBJECTIVE</b>To study the protective effect of Sarcandra glabra extract (SGE) on immune system in restrained mice.</p><p><b>METHOD</b>The male C57BL/6 mice were randomly divided into normal control group, stress control group, 125, 500 mg x kg(-1) SGE group. The spleen lymphocyte suspensions of each group were prepared. The parameters of spleen T cells subsets, NK cell and NKT cell proportion and number was detected by Flow cytometry.</p><p><b>RESULT</b>SGE regulated the balance of T cell subsets, increased the percent of NK cells and NKT cell proportion and number in restrained mice.</p><p><b>CONCLUSION</b>SGE has immunologic protective effect in restrained mice probably via the amelioration of immune cells proportion and number.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Stress, Psychological
/
Restraint, Physical
/
Drugs, Chinese Herbal
/
Killer Cells, Natural
/
Chemistry
/
T-Lymphocyte Subsets
/
Magnoliopsida
/
Allergy and Immunology
/
Natural Killer T-Cells
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2009
Type:
Article
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