Studies on chemical constituents of roasted seeds of Cassia obtusifolia / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the chemical constituents of the roasted seeds of Cassia obtusifolia to illuminate the change of its effective components before and after roasted.</p><p><b>METHOD</b>Compounds were separated by silica gel chromatography, and their structures were evaluated by spectral analysis and chemical evidence.</p><p><b>RESULT</b>Seven compounds were isolated from the ethanol extract. Their structures were identified as chrysophanol (1), physcion (2), 8-methoxylchrysophanol (3), beta-sitosterol (4), emodin (5), obtusin (6) and obtusifolin-2-O-beta-D-(6'-O-acetyl) glucopyranside (7).</p><p><b>CONCLUSION</b>Compounds 1-7 were isolated from the roasted seeds of C. obtusifolia for the first time, and compound 7 was a new compound.</p>