Surgical treatment for colorectal cancer with simultaneous hepatic metastasis / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 552-554, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-298551
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the indication of surgical treatment for primary colorectal carcer with simultaneous hepatic metastasis.</p><p><b>METHODS</b>116 colorectal cancer patients with simultaneous hepatic metastasis underwent surgery from January 1990 to December 2001. The data were analyzed using Statistical Package for the Social Sciences (Release 11.5, SPSS, Inc). The survival was estimated using Kaplan-Meier method, and the survival comparison was carried out using the log-rank test. Multivariate analysis was performed using Cox regression.</p><p><b>RESULTS</b>Totally, 116 patients received surgical resection for primary colorectal tumor, 18 of them underwent liver metastasis resection simultaneously. Postoperative complication developed in 14.7% of these patients with postoperative death in two patients. The overall 5-year survival rate was 14.29%. The 5-year survival rate of those who had liver metastasis resection was 32.12%. Multivariate analysis showed that liver metastasis resection, abdominal carcinomatosis, chemotherapy and intervention treatment were the most important prognostic factors.</p><p><b>CONCLUSION</b>Surgical resection of primary colorectal cancer with simultaneous resection of liver metastasis or with combined modality therapies such as chemotherapy and intervention treatment is effective to prolong patient's survival for primary colorectal cancer patient with simultaneous hepatic metastasis.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Rectal Neoplasms
/
Rectum
/
General Surgery
/
Adenocarcinoma
/
Antineoplastic Combined Chemotherapy Protocols
/
Proportional Hazards Models
/
Survival Rate
/
Follow-Up Studies
/
Chemotherapy, Adjuvant
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Oncology
Year:
2007
Type:
Article
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