Changes and clinical significance of serum Apelin in patients with severe sepsis and septic shock / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 131-135, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-298728
ABSTRACT
<p><b>OBJECTIVE</b>To explore the changes and clinical significance of serum Apelin in patients with severe sepsis and septic shock.</p><p><b>METHOD</b>We measured the serum level of Apelin with ELISA on different observation days (the 1st, 3rd, and 10th day obtaining the diagnosis) in 26 patients with severe sepsis and septic shock.</p><p><b>RESULTS</b>Serum Apelin significantly increased in sepsis patients when compared with the normal control group (P<0.01); The serum Apelin levels significantly changed among different observation days (P< 0.01). Serum Apelin level was significantly higher in patients with septic shock than those with severe sepsis (P<0.01).</p><p><b>CONCLUSION</b>Serum Apelin level changes in patients with severe sepsis and septic shock, which may provide clues in diagnosis and prognosis.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Shock, Septic
/
Time Factors
/
Blood
/
Enzyme-Linked Immunosorbent Assay
/
Mortality
/
Sepsis
/
Intercellular Signaling Peptides and Proteins
/
Apelin
Type of study:
Prognostic study
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2008
Type:
Article
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