Long term follow-up results of 199 patients with hypertrophic cardiomyopathy / 中华心血管病杂志
Chinese Journal of Cardiology
;
(12): 988-991, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-299543
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the associations among clinical characteristics and prognosis in patients with hypertrophic cardiomyopathy (HCM).</p><p><b>METHODS</b>Clinical and follow up data of 234 patients with HCM hospitalized in our institute from June, 1999 to March, 2006 were retrospectively analyzed.</p><p><b>RESULTS</b>A total of 199 out of 234 patients (85%) were followed up for (31.7 +/- 22.6) months. Twenty-one patients died during follow-up, and HCM-related deaths occurred in 19 patients including 11 (57.9%) patients with cardiac arrest, 7 (36.8%) patients with heart failure, 1 patient with stroke. The non-cardiac deaths were 1 accident death and 1 death due to acute pancreatitis. The survival rates of all followed up patients at 1, 2, 3, 4 and 5 years were 96.7%, 94.7%, 94.7%, 93.6% and 89.0%, respectively. Single risk factor analysis indicated that male gender, severe cardiac dysfunction, atrial fibrillation, sustained or non-sustained ventricular tachycardia (SVT or NSVT), left atrial enlargement, left ventricular outflow-track (LVOT) obstruction, family history were correlated with poor prognosis. Multifactor analysis showed SVT or NSVT (RR = 2.234, P < 0.001), NYHA class III - IV (RR = 1.964, P = 0.003) were independent risk factors for death. Among the cardio-cerebral death patients, echocardiography showed 14/19 (73.7%) Maron type III and 1/19 (5.2%) apical myocardial hypertrophy.</p><p><b>CONCLUSIONS</b>A relative benign long-term prognosis was shown in this group of HCM patients. Patients with apical myocardial hypertrophy, SVT or NSVT, NYHA class III - IV were facing increased risk of deaths.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Cardiomyopathy, Hypertrophic
/
Epidemiology
/
Survival Rate
/
Retrospective Studies
/
Risk Factors
/
Follow-Up Studies
/
Mortality
/
Diagnosis
Type of study:
Diagnostic study
/
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Cardiology
Year:
2007
Type:
Article
Similar
MEDLINE
...
LILACS
LIS