Clinical analysis of primary squamous cell carcinoma of the breast / 中华外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the clinicopathological features of primary squamous cell carcinoma (SCC) of breast and the diagnosis and treatment of the disease.</p><p><b>METHODS</b>The clinical, operative and pathological data from 7 cases of SCC of breast were retrospectively analysed.</p><p><b>RESULTS</b>Five patients complained of painless mass and two of them were accompanied with local pain. All patients were diagnosed as having SCC by fine-needle aspiration before operation. Two patients underwent modified radical mastectomy, and the others received radical mastectomy. Pathological examination showed primary squamous cell carcinoma of the breast with metastasis to axlliary lymph nodes in one patient. Follow-up of four patients revealed that two patients are living well and two patients died. Three patients lost to follow up.</p><p><b>CONCLUSION</b>The diagnosis of primary squamous cell carcinoma of the breast is dependent on pathological results. Radical mastectomy including modified radical mastectomy is most effective in the treatment of mammary SCC. Postoperative chemotherapy and radiation are necessary auxiliary therapy.</p>