Your browser doesn't support javascript.
loading
Study on supercritical CO2 extraction of xiaoyaosan and its GC-MS fingerprint / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 674-678, 2014.
Article in Chinese | WPRIM | ID: wpr-300170
ABSTRACT
To determine the optimum conditions of supercritical CO2 extraction of Xiaoyaosan, and establish its fingerprint by gas chromatography-mass spectrometry (GC-MS), the yield of extract were investigated, an orthogonal test was used to quantify the effects of extraction temperature, pressure, CO2 flow rate and time, and fingerprint analysis of different batches of extracts were by GC-MS. The optimal extraction conditions were determined as follows extraction pressure 20 MPa, extraction temperature 50 degrees C, CO2 flow rate 25 kg x h(-1), extraction time 3 h, and average yield 2.2%. The GC-MS fingerprint was established and 27 common peaks were found, whose contents add up to 81.89% of the total peak area. Among them, 21 compounds were identified, accounting for 53.20% of the total extract. The extraction process is reasonable and favorable for industrial production. The GC-MS method is accurate, reliable, reproducible, and can be used for quality control of supercritical CO2 extract from Xiaoyaosan.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Carbon Dioxide / Drugs, Chinese Herbal / Chemistry / Chromatography, Supercritical Fluid / Gas Chromatography-Mass Spectrometry / Methods Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2014 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Main subject: Carbon Dioxide / Drugs, Chinese Herbal / Chemistry / Chromatography, Supercritical Fluid / Gas Chromatography-Mass Spectrometry / Methods Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2014 Type: Article