Oncologic Outcome of Sacral Chordoma / 대한골관절종양학회지
The Journal of the Korean Bone and Joint Tumor Society
;
: 66-71, 2012.
Article
in Korean
| WPRIM
| ID: wpr-30028
ABSTRACT
PURPOSE:
We analyzed treatment result to examine the outcome for patients with sacral chordoma and to determine relevant prognostic factors. MATERIALS ANDMETHODS:
We retrospectively reviewed 19 patients with sacral chordoma seen at out institution between 1990 and 2010. There were 9 men and 10 women with mean age of 56 years. The average follow up was 63 months (range, 25-144 months). 15 patient received surgical treatment, six of these patient had wide, eight had marginal, one had intralesional margin and 4 patient treated with Radiation therapy only.RESULTS:
The disease free and overall survival rate for all 19 patients was 34.7% and 79.7% at 5-years, respectively. Statistical analysis using the log-rank test revealed no significant difference between the surgery and radiation therapy groups in overall survival (p=0.54). Nine of 19 patients had local recurrence at a median of 2.5 years postoperatively. Seven of these 9 patients had distant metastasis at a median of 4.5 years postoperatively. Among the variables, tumor size (p=0.033) and tumor involvement of above S3 (p=0.032) were independent prognostic factor for overall survival. Nine of 15 patients who received surgical treatment had postoperative complication such as voiding difficulty and incontinence.CONCLUSION:
Careful consideration of the patient general condition and predictable complication of the treatment might be the best way to improve patient's survival and quality of life.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Postoperative Complications
/
Quality of Life
/
Recurrence
/
Sacrum
/
Chordoma
/
Survival Rate
/
Retrospective Studies
/
Follow-Up Studies
/
Neoplasm Metastasis
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Language:
Korean
Journal:
The Journal of the Korean Bone and Joint Tumor Society
Year:
2012
Type:
Article
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