Expression of Runx2/Cbfa1 in the developing pulpo-dentinal complex of postnatal mice / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 373-376, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-300294
ABSTRACT
<p><b>OBJECTIVE</b>To study the expression of Runx2/Cbfa1 in the developing dentin and differentiating odontoblasts.</p><p><b>METHODS</b>A postnatal mice teeth developing model was built histologically. Immunohistochemical technique was adopted to determine the expression of Runx2/Cbfa1 in the developing pulpo-dentinal complex in mice.</p><p><b>RESULTS</b>Runx2/Cbfa1 was merely present in predentin in the exact and before the 11th day's postnatal stages. Meanwhile, it was positively located in odontoblasts and dental pulp cells in root region, but negatively in coral part after the 11th day's stages.</p><p><b>CONCLUSION</b>Runx2/Cbfa1 may play an important role in the deposing of tooth dentin and in the differentiating of odontoblasts and pulp cells.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tooth
/
Cell Differentiation
/
Dental Pulp
/
Dentin
/
Core Binding Factor Alpha 1 Subunit
/
Odontoblasts
Type of study:
Prognostic study
Limits:
Animals
Language:
Chinese
Journal:
West China Journal of Stomatology
Year:
2005
Type:
Article
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