Effect of static magnetic field on bone morphogenetic protein-2 in periodontal membrane of experimental periodontitis rat / 华西口腔医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the effect of static magnetic field on expression of bone morphogenetic protein-2(BMP-2) in the periodontal membrane of experimental periodontitis rat.</p><p><b>METHODS</b>Experimental periodontitis of rat was formed by ligaturing the neck of rat teeth and feeding sugar of high concentration. The magnet which the intensity of magnetic field was 0.12 tesla was put into their cheeks. The rats were sacrificed at 2nd day, 4th day and 7th day, respectively. Immuno-histochemical techniques were used to evaluate the change of BMP-2 expression.</p><p><b>RESULTS</b>BMP-2 was mainly found in the plasma of fibroblast, osteoblast, cementocyte and odontoblast separately. There was not clearly difference between the periodontitis group and the normal group, but BMP-2 in the experimental group treated with static magnetic field was higher than the two groups.</p><p><b>CONCLUSION</b>Static magnetic field plays an important role in repairing and remodeling of periodontitis.</p>