Expression and significance of cyclin D1 in human adenoid cystic carcinoma / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 191-193, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-300340
ABSTRACT
<p><b>OBJECTIVE</b>To observe the expression of cyclin D1 in human adnoid cystic carcinoma and its correlation with clinical characters.</p><p><b>METHODS</b>The expression of cycline D1 was evaluated with immunohistochemical method in forty-one cases of human adnoid cystic carcinoma, 15 cases of PA and 12 cases of normal salivary gland tissue.</p><p><b>RESULTS</b>The expression of cyclin D1 in normal tissue was negative, significantly different from PA and ACC (P < 0.05). The expression level of PA was significantly lower than ACC (P < 0.05). High expression of cyclin D1 was correlated with clinical stage and histological classification (P < 0.05), but not with sex, age, tumor site, recurrence, metastasis.</p><p><b>CONCLUSION</b>High expression of cyclin D1 promotes the formation and development of ACC.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Salivary Gland Neoplasms
/
Carcinoma
/
Carcinoma, Adenoid Cystic
/
Cyclin D1
Limits:
Female
/
Humans
Language:
Chinese
Journal:
West China Journal of Stomatology
Year:
2005
Type:
Article
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