Research advances in mesenchymal stem cell-derived exosomes in treatment of brain injury / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 1285-1290, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-300406
ABSTRACT
Mesenchymal stem cell (MSC) transplantation is considered one of the most promising therapeutic strategies for the repair of brain injuries and plays an important role in various links of nerve repair. Recent studies have shown that MSC-derived exosomes may dominate the repair of brain injuries and help to promote angiogenesis, regulate immunity, inhibit apoptosis, and repair the nerves, and therefore, they have a great potential in the treatment of brain injuries in neonates. With reference to these studies, this article reviews the mechanism of action of exosomes in the repair of brain injuries and related prospects and challenges, in order to provide new directions for the treatment of brain injuries in neonates with stem cells.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Therapeutics
/
Brain Injuries
/
T-Lymphocytes
/
Apoptosis
/
Neovascularization, Physiologic
/
Mesenchymal Stem Cell Transplantation
/
Allergy and Immunology
/
Exosomes
/
Inflammation
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2017
Type:
Article
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