Gastric Microbiota and Gastric Cancer
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
;
: 73-81, 2016.
Article
in Korean
| WPRIM
| ID: wpr-30054
ABSTRACT
The stomach had been recognized as an organ where many bacteria cannot survive due to the presence of gastric acid. However, a number of bacteria have been detected after the discovery of Helicobacter pylori with recent advances in nucleotide sequencing techniques and bioinformatics. These include Proteobacteria, Firmicutes, Bacteroidetes, Actinobacteria and Fusobacteria. Several animal studies suggested that the imbalance of gastric microbiotas could be associated with the development of gastric cancer. Changes in the composition of the gastric microbiota may increase the production of N-nitroso compounds, which is known to be a carcinogen. Further studies on the actual function and proteomics of gastric microbiota could be beneficial for prevention, early diagnosis, and new treatment strategies of gastric cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stomach
/
Stomach Neoplasms
/
Bacteria
/
Helicobacter pylori
/
Actinobacteria
/
Computational Biology
/
Proteobacteria
/
Proteomics
/
Bacteroidetes
/
Fusobacteria
Type of study:
Diagnostic study
/
Screening study
Limits:
Animals
Language:
Korean
Journal:
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Year:
2016
Type:
Article
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