The distribution and pathogen of bacteria infection in patients after liver transplantation / 中华外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To find out the epidemiology of bacteria infection after orthotopic liver transplantation (OLT).</p><p><b>METHOD</b>Postoperative bacteria infection of 451 OLT cases were retrospectively analyzed.</p><p><b>RESULT</b>Bacteria infection were detected in 239 OLT cases, and the infection rate was 52.9%. Sum up to 304 bacilli lines were separated from all above cases. Among them, the detectable Gram-positive bacilli (G(+)) accounted for 59.9% (182/304), while Gram-negative bacilli (G(-)) accounted for 40.2% (122/304). The impressionable organ were respiratory tract and bile duct, which occupying 81.5% (248/304) and 15.1% (46/304) among all infective cases respectively. The main infected strain were G(+) bacteria in respiratory tract, account for 65.3%; while G(-) bacteria were mainly in bile duct, account for 60.9%. There was significant difference between each other (P = 0.018).</p><p><b>CONCLUSIONS</b>The bacteria infection rate was high after OLT, and the main infected strain was the G(+) bacteria. Most fo them were the opportunistic pathogenic bacteria and the antibiotic multi-resistant bacteria. The bacteria category was significantly related to the infected tissue, according to which we could adopt corresponding antibacterial approach.</p>