Clinical analysis in diagnosis and treatment of 11 patients with hereditary renal cell carcinoma / 中华外科杂志
Chinese Journal of Surgery
;
(12): 963-965, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-300577
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the diagnosis and treatment of hereditary renal cell carcinoma.</p><p><b>METHODS</b>Clinical data of 11 patients with hereditary renal cell carcinoma were analyzed retrospectively. Eight patients were male and 3 were female, age ranged from 32 to 67 (mean age 48 years). Four cases were bilateral renal cell carcinoma, and 4 were multiple renal cell carcinoma. Two cases were diagnosed as Von Hippel-Lindau syndrome, 6 as familial clear cell renal cell cancer, and 3 as hereditary papillary renal carcinoma.</p><p><b>RESULTS</b>Ten patients performed nephron-sparing surgery and/or radical nephrectomy and 1 had no operation. The patients were followed up from 12 to 114 months. Tumor recurrence was observed in 4 patients, 1 patient died of tumor metastasis, and 2 died of other causes. Four patients survived free of tumor.</p><p><b>CONCLUSIONS</b>Hereditary renal carcinoma appears in the youth, and it is predominantly multiple and bilateral. Nephron-sparing surgery is the standard method of treatment for the patients.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
General Surgery
/
Carcinoma, Renal Cell
/
Retrospective Studies
/
Diagnosis
/
Genetics
/
Kidney Neoplasms
Type of study:
Diagnostic study
/
Observational study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Surgery
Year:
2006
Type:
Article
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