The study of relationship between nuclear metrix protein 22 urinary level and the grade and stage of bladder transitional cell carcinoma / 中华外科杂志
Chinese Journal of Surgery
;
(12): 681-683, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-300625
ABSTRACT
<p><b>OBJECTIVE</b>To assess the relationship between nuclear matrix protein (NMP) 22 urinary level and the grade and stage of bladder transitional cell carcinoma.</p><p><b>METHODS</b>From June 1999 to March 2005 642 patients underwent NMP22 test, and then the test by cystoscope and pathology were performed in 1 week to 1 month. According to the pathological grade, the patients were divided into 3 groups group G(1) 69 cases, male 58 and female 11; group G(2) 375 cases, male 255 and female 120; group G(3) 198 cases, male 143 and female 55. And the difference of NMP22 between each group were compared. Meanwhile, according to pathological stage, 239 patients were divided into 3 groups group PT(1) 121 cases, male 76 and female 45; group PT(2) 65 cases, male 37 and female 28; group PT(3) 53 cases, male 29 and female 24. And the difference of NMP22 between each group were compared.</p><p><b>RESULTS</b>The concentrations of NMP22 had significant difference between the 3 groups which divided according to pathological grade (Kruskal-Wallis test chi(2) = 67.547, P < 0.001); The concentrations of NMP22 had significant difference between the 3 groups which divided according to pathological stage (Kruskal-Wallis test chi(2) = 20.629, P < 0.001).</p><p><b>CONCLUSIONS</b>There is a relation between NMP22 urinary level and the grade and stage of bladder transitional cell carcinoma.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Urine
/
Urinary Bladder Neoplasms
/
Nuclear Proteins
/
Carcinoma, Transitional Cell
/
Biomarkers, Tumor
/
Neoplasm Staging
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Surgery
Year:
2006
Type:
Article
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