Regulatory genes controlling neural stem cells differentiation into neurons / 神经科学通报·英文版
Neuroscience Bulletin
;
(6): 294-300, 2006.
Article
in English
| WPRIM
| ID: wpr-300930
ABSTRACT
The recent progress in neural stem cells (NSCs) research has shed lights on possibility of repair and restoration of neuronal function in neurodegenerative diseases using stem cells. Induction of stem cells differentiate into mature neurons is critical to achieve the clinical applications of NSCs. At present, molecular mechanisms modulating NSC differentiation are not fully understood. Differentiation of stem cells into neuronal and glial cells involves an array of changes in expression of transcription factors. Transcription factors then trigger the expression of a variety of central nervous system (CNS) genes that lead NSCs to differentiate towards different cell types. In this paper, we summarized the recent findings on the gene regulation of NSCs differentiation into neuronal cells.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Neuroscience Bulletin
Year:
2006
Type:
Article
Similar
MEDLINE
...
LILACS
LIS