Epigenetics and neural stem cell commitment / 神经科学通报·英文版
Neuroscience Bulletin
;
(6): 241-248, 2007.
Article
in English
| WPRIM
| ID: wpr-300957
ABSTRACT
Neural stem cell is presently the research hotspot in neuroscience. Recent progress indicates that epigenetic modulation is closely related to the self-renewal and differentiation of neural stem cell. Epigenetics refer to the study of mitotical/meiotical heritage changes in gene function that cannot be explained by changes in the DNA sequence. Major epigenetic mechanisms include DNA methylation, histone modification, chromatin remodeling, genomic imprinting, and non-coding RNA. In this review, we focus on the new insights into the epigenetic mechanism for neural stem cells fate.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Stem Cells
/
Cell Differentiation
/
Genomic Imprinting
/
DNA Methylation
/
Chromatin Assembly and Disassembly
/
Epigenesis, Genetic
/
Neurons
Limits:
Animals
/
Humans
Language:
English
Journal:
Neuroscience Bulletin
Year:
2007
Type:
Article
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