Chelation of GRP78 with Lead and Its Localization Changes in the Astroglia of Rats Exposed to Lead

ZHANG YING; YE LIPING; WANG BIAO; LI YAN; SUN LIGUANG

Chelation of GRP78 with Lead and Its Localization Changes in the Astroglia of Rats Exposed to Lead / 华中科技大学学报（医学）（英德文版）

ZHANG YING; YE LIPING; WANG BIAO; LI YAN; SUN LIGUANG.

Journal of Huazhong University of Science and Technology (Medical Sciences) ; (6): 492-497, 2009.

Article in Chinese | WPRIM | ID: wpr-301286

ABSTRACT

ABSTRACT

remarkably increase when it transferred from ER to the cytosol around the nuclei 24 h after treatment with Pb. It is concluded that GRP78 in astroglia could strongly chelate with Pb ions and it might be a target protein of Pb.

lead; astroglia; GRP78; chelation

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Journal of Huazhong University of Science and Technology (Medical Sciences) Year: 2009 Type: Article

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