Research advances in Sirt1 gene / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 782-785, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-301608
ABSTRACT
As the most homologic homologue of silent information regulator 2 of yeast, Sirt1 gene is extensively expressed in mature tissues, and is rich in early embryo and reproductive cells. It is involved in the regulation of gene transcription, energy metabolism and cell aging. It promotes fat mobilization in adipocytes and glucose production in liver and regulates insulin secretion in islet beta cell. Furthermore, Sirt1 gene is an essential endogenous apoptosis inhibitor. In future, it may be used as new drug targets or applied in other disease management modalities.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Sirtuin 1
/
Genetics
/
Metabolism
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2009
Type:
Article
Similar
MEDLINE
...
LILACS
LIS