Basic and clinical research on paraneoplastic pemphigus / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 654-658, 2009.
Article
in Zh
| WPRIM
| ID: wpr-301632
Responsible library:
WPRO
ABSTRACT
Paraneoplastic pemphigus (PNP) is an autoimmune blistering skin disease associated with neoplasms. Clinically, it is characterized by severe mucosal erosions and various cutaneous lesions. Suprabasal acantholysis and cleft with scattered necrotic keratinocytes are the unique histopathological features of PNP. The pathogenic autoantibodies existed in PNP sera, and their production was correlated with the associated tumor. Early detection and resection of the tumor are essential for the treatment of the disease.
Full text:
1
Index:
WPRIM
Main subject:
Paraneoplastic Syndromes
/
Pemphigus
Type of study:
Screening_studies
Limits:
Humans
Language:
Zh
Journal:
Acta Academiae Medicinae Sinicae
Year:
2009
Type:
Article