Progress on bone marrow mesenchymal stem cells transplantation for spinal cord injury / 中国骨伤
China Journal of Orthopaedics and Traumatology
;
(12): 437-440, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-301798
ABSTRACT
Bone marrow mesenchymal cells (BMSCs) are regarded as donor cells in cell transplantation therapies for spinal cord injury (SCI) for they have the ability of favourable proliferation and multi-directional differentiation, and are easily isolated and culturd and have less immunological reaction. It has been confirmed that subarachnoid space injection is the most ideal delivery technique of BMSCs. Bone marrow mesenchymal stem cells transplantation is safe and its reconditioning role is certain for SCI in early clinical application. The mechanism of BMSCs promoting functional recovery after SCI is probably concerned with vicarious function, nerve trophism, immunosuppression and promoting axonal regeneration by BMSCs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Spinal Cord Injuries
/
General Surgery
/
Bone Marrow Cells
/
Cell Biology
/
Mesenchymal Stem Cell Transplantation
/
Mesenchymal Stem Cells
/
Methods
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
China Journal of Orthopaedics and Traumatology
Year:
2014
Type:
Article
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