Dendritic cells and acute myeloid leukemia / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1148-1152, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-302330
ABSTRACT
Dendritic cells can be derived from leukemia cells and normal precursor cells in the patients with acute myeloid leukemia (AML). Dendritic cells may capture leukemia antigen in bone marrow or lymph nodes, and present leukemia common antigen to stimulate proliferation of specific CD8(+) T cells, playing anti-leukemia effect. Dendritic cells for clinical and experimental use are transformed from leukemia cells and peripheral blood mononuclear cells and loaded in vitro with leukemia -specific or tumor common antigen, play a therapeutic role after reinfusion. This article reviews dendritic cells in the immunotherapy of AML.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Therapeutics
/
Dendritic Cells
/
Leukemia, Myeloid, Acute
/
Allergy and Immunology
/
Immunotherapy
Limits:
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2014
Type:
Article
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